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Anti-cholesterol statins have 'less than imagined' side effects risk

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Around seven to eight million people in the UK take statins to cut their chance of heart attack and stroke.

Experts said up to half of people stop taking the medication, cut the dose or take them irregularly due to issues with muscle pain and other side-effects, such as digestive problems, issues with sleep and headaches.

In research published in the European Heart Journal, which analysed studies on more than four million people, experts put the true level of statin intolerance – where patients develop side effects from the drug- at between six percent and 10 percent.

Statins are a group of medicines that can help lower the level of low-density lipoprotein cholesterol – often referred to as “bad cholesterol” – in the blood.

LDL cholesterol is linked to cardiovascular disease, which can increase the chance of strokes and heart attacks, and death.

In the study, led by Professor Maciej Banach, of the Medical University of Lodz and the University of Zielona Gora, Poland, on behalf of the Lipid and Blood Pressure Meta-Analysis

Collaboration and the International Lipid Expert Panel, experts analysed 176 studies with 4,143,517 patients worldwide.

People were typically aged around 60 in the study and 40 percent were female. Prof Banach said the findings showed that life-saving “statins can be used safely in most patients”.

Researchers found that people who were older, female, of black or Asian background, obese, suffering from diabetes, under-active thyroid glands, or chronic liver or kidney failure were more likely to be statin intolerant.

People on some drugs, such as for high blood pressure, and those who drank lots of alcohol also had a higher risk of statin intolerance.

Prof Banach added doctors need to confirm whether symptoms are indeed caused by statins, “and secondly, to evaluate whether it might be patients’ perceptions that statins are harmful – which could be responsible for more than 50 per cent of all symptoms, rather than the drug.

He added: “These results clearly show that patients needn’t be afraid of statin therapy as it is very well tolerated in as much as 93 percent.

“Patients need to know that statins may prolong their life, and in cases where side-effects appear, we have enough knowledge to manage these.

“The most important message to patients is that they should keep on taking statins according to the prescribed dose, and discuss any sideeffects with their doctor, rather than discontinuing the medication.”



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For online betting lovers, renting the Kubet bookie is no longer a strange name. Because This is one of the bookmakers, many appreciate its quality and prestige. At the same time, the variety of games and betting forms is also one factor that attracts players.

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Boxed Packaged Goods: How To Choose The Appropriate Material

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How To Choose The Appropriate Material For Your Boxed Packaged Goods? If you are someone who runs a small business that sells apparel, shoes, food and beverages, cosmetics, and electronics online? And you want to establish a name for yourself in the market by offering worldwide shipping? We’ve got you covered in this article, as we go through some of the best Boxed Packaged Goods you may use. We’ll also explain which kind of packaging boxes are best for different products. So, go ahead and read the entire article on Boxed Packaged Goods.

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Ruud van Nistelrooy makes next job decision as Man Utd plan coaching appointment

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That decision failed to pay off, however, with the Red Devils sacking Moyes after just 10 months in charge.

After the current West Ham boss came Van Gaal, who arrived with big things expected due to his past success at the likes of Barcelona and Ajax.

Giggs was hoping to get the Red Devils job himself, which was why he stayed, but both ended up leaving nearly six years ago.

When Jose Mourinho took over, he opted to maintain his close relationship with Rui Faria – who had previously worked under him at clubs such as Real Madrid and Chelsea.

Fair departed in the summer of 2018, though, with Michael Carrick then given a place on Mourinho’s bench.

Carrick stayed to work under Ole Gunnar Solskjaer, with the Norwegian also regularly picking up the thoughts of Phelan and Kieran McKenna throughout his spell in the dugout.

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