Nation
Blood pressure recall: Pfizer recalls Accuretic, generic drugs for cancer risk due to nitrosamine
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Pfizer is voluntarily recalling several lots of blood pressure medication due to elevated levels of nitrosamine, which can increase the risk of cancer.
The company said it is recalling six lots of Accuretic tablets that it distributed, one lot of quinapril and hydrochlorothiazide tablets and four lots of quinapril HCl/ hydrochlorothiazide tablets because the level of nitrosamine was above the acceptable daily intake.
Nitrosamines are common in water and foods, including cured and grilled meats, dairy products and vegetables, Pfizer said in its recall notice.
Last September, Pfizer recalled all lots Chantix smoking cessation drug for high levels of nitrosamine.
“Everyone is exposed to some level of nitrosamines. These impurities may increase the risk of cancer if people are exposed to them above acceptable levels over long periods of time,” the company said.
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Pfizer said it is “not aware of reports of adverse events that have been assessed to be related to this recall.”
“Although long- term ingestion of N-nitroso-quinapril may be associated with a potential increased cancer risk in humans, there is no immediate risk to patients taking this medication,” Pfizer said.
Health care professionals advise patients to consult with their doctors or pharmacists before discontinuing one of the recalled blood pressure medicines or finding an alternative treatment.
Discontinuing a recalled drug could cause more immediate harm than staying on the medication.
Blood pressure medicine recall
The affected items are 90-count bottles.
Accuretic (quinapril HCl/hydrochlorothiazide) tablets, 10/12.5 mg
- NDC: 0071-3112-23; Lot number: FG5379; Expiration date: August 2024
- NDC: 0071-0222-23; Lot number: EA6686; April 2022
Accuretic (quinapril HCl/hydrochlorothiazide) tablets, 20/12.5 mg
- NDC: 0071-5212-23; Lot number: FG5381; Expiration date: August 2024
- NDC: 0071-0220-23; Lot number: EA6665; Expiration date: April 2022
- NDC: 0071-0220-23; Lot number: CN0640; Expiration date: April 2022
Accuretic (quinapril HCl/hydrochlorothiazide) tablets, 20/25 mg
- NDC: 0071-0223-23; Lot number: ET6974; Expiration date: February 2023
Quinapril and hydrochlorothiazide tablets, 20/25 mg:
- NDC: 59762-5225-9; Lot number: FE3714; Expiration date: February 2023
Quinapril HCl/hydrochlorothiazide tablets, 20/12.5 mg:
- NDC: 59762-0220-1; Lot number: DN6931; Expiration date: March 2023
- NDC: 59762-0220-1; Lot number: ED3904; Expiration date: March 2023
- NDC: 59762-0220-1; Lot number: ED3905; Expiration date: March 2023
Quinapril HCl/hydrochlorothiazide tablets, 20/25 mg
- NDC: 59762-5225-9; Lot number: FE3714; Expiration date: February 2023
What to do if you take the recalled blood pressure medication
According to Pfizer, patients who are taking one of the affected products should consult with their healthcare provider or pharmacy to determine if they have the affected product.
Patients with the affected product can call 888-843-0247 on weekdays from 8 a.m. to 5 p.m. ET for instructions on how to return their product and obtain reimbursement for their cost.
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Uber, Lyft made safety improvements, but many of those protect riders more than drivers. But drivers are also in danger.
Naomi Ogutu
Opinion contributor
I’ve been a rideshare driver in New York City for six years, and I take pride in my job and helping my passengers get where they need to go safely. But my safety is not a guarantee. I’m a mom of three. I need to know that I’ll make it home to my kids at the end of each night.
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Business
'A bad déjà vu': Under the crush of Western sanctions, Russians fear a return to dark economic days
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Harsh sanctions from Western nations on Russia have reminded citizens of the country’s 1998 debt crisis.
By Anna Nemtsova
USA TODAY
- McDonalds and other American businesses have closed in Russia amid its invasion into Ukraine.
- One expert estimates more than 200,000 Russians have left the country since the start of the war.
- To counter economic turmoil, Putin has demand “unfriendly” countries pay for natural gas exports in rubles.
The once bustling corner of Moscow’s central Tverskaya Street looked deserted on Wednesday, as Russia’s first-ever McDonald’s franchise – opened in 1990 in a move that symbolized the Soviet Union’s opening to the West – shut its doors.
A large mural depicting a giant, Soviet-era medal – the Order of Victory, the highest military decoration awarded in World War II — loomed over over the empty sidewalk.
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The lone No. 1 seed still alive heading into the Elite Eight, Kansas needs only a win against No. 10 Miami (Fla.) to book a spot in the Final Four.
No. 2 Duke and coach Mike Krzyzewski can make one last Final Four and chase one final national championship by beating No. 4 Arkansas.
No. 2 Villanova can reach the national semifinals for the third time in six tournaments by winning what should be a defense-dominated brawl against No. 5 Houston.
And after beating No. 4 UCLA in the Sweet 16, No. 8 North Carolina is one win from reaching the Final Four under first-year coach Hubert Davis.
If everything goes according to plan, this year’s Final Four will consist of some of the biggest names in the history of the sport.
But the last week has taught us that this year’s NCAA Tournament will inevitably deviate from the script.
So look for the Jayhawks to be shocked in the Elite Eight, as the Bill Self collection of tournament collapses adds another painful chapter. Based on how things have gone through three rounds, Arkansas is a lock to send Krzyzewski into retirement one game shy of the Final Four. Villanova may be a two-time champion under Jay Wright, but the Wildcats will be smothered by Houston.
And, of course, the Tar Heels will lose to the team that embodies the wackiness and uncertainty of this entire tournament.
Saint Peter’s stands at the precipice of another outlandish achievement: being the first No. 15 seed — the first seed lower than No. 11, in fact — to reach the Final Four.
The Peacocks will be the underdog once again come Sunday, when they’ll match against a deeper and more talented opponent with decades of history to more than overshadow the Peacocks’ three-game run.
But beating another college basketball giant will simply take what we already know the Peacocks can bring to the table: Saint Peter’s reached the Elite Eight with energy, aggressiveness and composure, following the model set by unflappable coach Shaheen Holloway, and that same combination will give the Peacocks a chance at etching themselves into an even more permanent place in NCAA Tournament history.
“We’re happy but don’t mistake, we’re not satisfied, we’re not satisfied at all,” said guard Doug Edert. “The job is not finished. We feel like we belong and the more games we win the more confidence we build.”
That sounds like bad news for the Tar Heels, who might’ve righted the ship after a poor start to ACC play but could be the latest blueblood to the Peacocks’ formula.
At some point, the magic has to run out — for Saint Peter’s, which somehow keeps stacking upsets of higher-ranked opponents, and for the tournament at large, which has been wackier than ever but could suddenly snap back to the status quo.
But this March has not gone according to plan. Several big names lost early. Others failed to get out of the second round. The story of this year’s tournament has been upsets, shockers, letdowns, unpredictable officiating and unpredictability, period — why should the next two days be any different?
Follow colleges reporter Paul Myerberg on Twitter @PaulMyerberg
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