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High cholesterol: 'Exciting' new research on extra benefit of taking statins

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Parkinsonism symptoms include a tremor, slowness of movement, and muscle stiffness, with Parkinson’s disease being one of the better known causes. Parkinson’s disease is a progressive neurological condition that affects more than 137,000 Britons; each year, there are approximately 17,300 new diagnoses of Parkinson’s in people aged 45 and above, according to the National Institute for Health and Care Excellence (NICE).

On March 23, 2022, a new research paper suggested that “older people taking statin drugs have a lower chance of developing parkinsonism later compared to people who were not taking statins”.

Published in the American Academy of Neurology journal, the study’s lead author, Dr Shahram Oveisgharan, of Rush University Medical Center in Chicago, commented on the findings.

“Our results suggest people using statins may have a lower risk of parkinsonism and that may be partly caused by the protective effect statins may have on arteries in the brain.

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“Our results are exciting, because movement problems in older adults that come under the umbrella of parkinsonism are common, often debilitating and generally untreatable.”

The research details

The study included 2,841 people who averaged around 76 years of age; they did not have parkinsonism at the start of the research.

Of those, 936 people (33 percent) were taking statins, which is mainly prescribed to lower unhealthy cholesterol levels.

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Thus, the researchers concluded that people taking statins – after accounting for age, sex, and vascular risks – were 16 percent at lower risk of developing parkinsonism symptoms six years later.

Dr Oveisgharan added: “More research is needed, but statins could be a therapeutic option in the future to help reduce the effects of parkinsonism in the general population of older adults. Not just people with high cholesterol or who are at risk for stroke.”

One weakness of the research project was that the parkinsonism evaluations were not conducted by movement disorder specialists.

As such, cases of parkinsonism may have been misclassified, thereby affecting the results.

Regardless, the current use of statins to lower cholesterol levels has been well researched and been shown to be effective.

For example, the cholesterol charity Heart UK pointed out that statins could reduce cholesterol levels by up to 50 percent.



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Ruud van Nistelrooy makes next job decision as Man Utd plan coaching appointment

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That decision failed to pay off, however, with the Red Devils sacking Moyes after just 10 months in charge.

After the current West Ham boss came Van Gaal, who arrived with big things expected due to his past success at the likes of Barcelona and Ajax.

Giggs was hoping to get the Red Devils job himself, which was why he stayed, but both ended up leaving nearly six years ago.

When Jose Mourinho took over, he opted to maintain his close relationship with Rui Faria – who had previously worked under him at clubs such as Real Madrid and Chelsea.

Fair departed in the summer of 2018, though, with Michael Carrick then given a place on Mourinho’s bench.

Carrick stayed to work under Ole Gunnar Solskjaer, with the Norwegian also regularly picking up the thoughts of Phelan and Kieran McKenna throughout his spell in the dugout.

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High cholesterol: Blood pressure drug linked to significant reduction in good cholesterol

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“Though they’re commonly used to treat different forms of heart disease, beta-blockers can significantly reduce HDL levels.”

Among the beta-blockers that cause this are Corgard (nadolol), Inderal (propranolol), Tenormin (atenolol), Zebeta (bisoprolol).

These drugs are widely used in the treatment of angina, heart failure, atrial fibrillation, heart attack and high blood pressure.

But despite concerns about their effect on cholesterol, scientists stress that the benefits of beta-blockers far outweigh the risks.

VeryWell Health adds: “If your beta-blocker affects your cholesterol significantly, your doctor may lower your dose or switch you to a different medication.”



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Max Verstappen and Sergio Perez not on same page over Saudi Arabia GP after missile attack

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However, after a four-hour meeting between race officials and the teams, it was confirmed the race would go ahead despite the attack. It had been reported that a number of the competing drivers were concerned for their safety following the nearby explosion.

Despite this, an agreement was finally reached to race at 2:30am local time, after team chiefs left the lengthy meeting to confirm: “We will be racing.” A statement from Formula 1 confirmed Sunday’s race would go ahead as planned. It read: “Formula 1 has been in close contact with the relevant authorities following the situation that took place today. The authorities have confirmed that the event can continue as planned and we will remain in close contact with them and all the teams and closely monitor the situation.”

Unsurprisingly, there were a number of mixed views on whether the race should go ahead, and this is clearly apparent in the Red Bull setup. This comes after advisor Helmut Marko revealed that drivers Verstappen and Perez are not on the same page when it comes to racing.

JUST IN: F1 drivers ‘had concerns’ about Saudi Arabia GP as new details emerge after missile attack

On the issue, Marko told Sky Germany: “Max is a bit more relaxed about it. Perez is a little bit scared, but when you live in Mexico City there’s not much more security. We have the pandemic, we have the war in Europe and now we have a missile attack 20 kilometres away. This is no longer normal or pleasant.”

Ahead of tomorrow’s race though, the Austrian advisor is firmly on the side of Verstappen and the race officials, supporting the idea of the race taking place. He commented: “I really think it’s the right thing to do. As I said, these drone attacks are common, I think. They have a very good defence system. Why this one didn’t work remains to be seen. It’s not the first drone, after all. But it’s the first one to strike on such a scale.”

The attack took place during Friday’s first practice session, and it was Red Bull’s star man Verstappen who was one of the first to realise something was wrong after reporting on his team radio that he could ‘smell burning’. Initially, the Dutchman thought the smell was coming from either his or one of his rival’s cars, however it then became clear that an explosion had taken place just a few miles from the track.

Giving an insight into Verstappen’s initial worries, Marko said: “Max radioed us, he thought his car had caught fire because there was an intense burning smell. We were informed a drone had been sent from Yemen. The Saudis have a defence system and for some reason the drone was not intercepted.”



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